Consumer Medicine Information (CMI) about Pramin (metoclopramide hydrochloride) intended for persons living in Australia. Pramin – Product Information 3 Epilepsy. The frequency and severity of seizures may be increased in epileptic patients given metoclopramide. Pramin (metoclopramide hydrochloride) is an anti-emetic used to control nausea and vomiting associated with different conditions, and to activate stomach contractions. 1 What Metoclopramide tablets are and what they are used for. Metoclopramide tablets are an antiemetic. It works on a part of your brain that prevents you from feeling sick (nausea) or being sick (vomiting). Pramin Tablet may also be used for purposes not listed in this medication guide. Pramin Tablet contains Metoclopramide Hydrochloride Monohydate as an active ingredient. Pramin Tablet works by blocking a natural substance called dopamine. Detailed Metoclopramide dosage information for adults and children. Includes dosages for Gastroesophageal Reflux Disease, Gastroparesis, Nausea/Vomiting - Chemotherapy Induced and more; plus renal, liver and dialysis adjustments. Metoclopramide is a medication used mostly for stomach and esophageal problems. It is commonly used to treat and prevent nausea and vomiting, to help with emptying of the stomach in people with delayed stomach emptying, and to help with gastroesophageal reflux disease. It is also used to treat migraine headaches. Metoclopramide oral is also used to treat gastroparesis (slow stomach emptying) in people with diabetes, which can cause heartburn and stomach discomfort after meals. Metoclopramide injection is used to treat severe diabetic gastroparesis.